Cellular responses to toot hautotransplantation: Explanations for regeneration, repair and failure healing.

Jens Ove Andreasen

Keynote lecture - Friday, May 20, 2022

About author:

Dr. Andreasen received his dental degree from the Royal Dental College, Copenhagen, in 1959. He did his postgraduate training in Oral and Maxillofacial Surgery at the University Hospital in Copenhagen, where he now is an associate Professor.
Dr. Andreasen has authored 400 publications and 12 textbooks, covering topics such as dental traumatology, tooth replantation and autotransplantation, tooth eruption and tooth impaction. In relation to traumatology the Textbook and Color Atlas of Dental Traumatology is now in its 5th edition and include 62 contributors.
He founded the interactive Dental Trauma Guide in 2008 which is now being used in 180 countries. It contains information of a series of prospective long term studies of all types of traumatic dental injuries carried out at the trauma center and Department of Oral and Maxillo-Facial Surgery as well as information from 50 animal experiments reproducing treatment scenarios of various dental traumas affecting primary as well as permanent teeth.
Dr. Andreasen has received four honorary doctorate degrees and has been an invited lecturer in 49 countries.


Abstract of the lecture:

Autotransplantation of a developing tooth represents an acute seveřance of the vascular supply to the pulp and periodontium and starts immediately healing events from neighboring tissue. If circulation is established within a few days it will result in regeneration via stem cells residing in th eoriginal tissue. If revascularization is delayed, a repair process will také place, here cementum PDL and bone is replacing the original pulp tissue. Finally, infection may occur in the traumatized tissue leading to revascularization failure.


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